What You Need to Know About Skin Discoloration

woman with skin discoloration



Hyperpigmentation, skin discoloration, melanin expression—call it what you will: when we talk about skin discoloration in relation to skin health, we typically are referring to the effects of melanin in the skin. Melanin is produced within the deepest layer of the epidermis by melanocytes and while different kinds of melanin are produced, they all relate to one thing: skin pigment. Melanin provides color for your skin. We’re going to take a closer look at the role of melanin expression in the skin and how imbalances can affect discoloration due to age and environmental factors.



In personal care spaces, skin discoloration usually refers to unevenness in color and variances in shades of your skin pigment. It covers a wide range, from freckles to age spots and so on. Discoloration happens when environmental or genetic factors prompt excess melanin production in the skin. Let’s start with a closer look at environmental factors.


Sun exposure

You’ve probably heard melanin claims in relation to tanning and evening skin tone since melanin is key to mitigating the effects of UV radiation. Your skin tries to produce enough melanin to protect your body from UV radiation but, with extended exposure to UV rays, that production can become accelerated and uneven. This process is called photoaging and recent research has strengthened its link to skin aging.1 It can also be an increasing factor as you age since your skin has been exposed to the sun more.2



There are several links between your health and your stress level, and your skin is no different. Some skin conditions can be exasperated by increased hormones released by the body under stress, many of which can require medical intervention to treat. However, stress also causes more agitation3 which can, in turn, cause increased irritation and appear as a difference in skin color on your skin.



Skin can get aggravated by pollutants, allergens, bacteria, and other environmental factors that then cause irritation that can result in pigment changes.



Sun exposure and stress can both lead to inflammation in the skin, along with other factors such as environment, allergies, injury, and a variety of skin conditions, among many others.4



Often, pregnancy can release hormones that can result in pigmentation changes in the skin. The most common instance of this is a type of melasma called chloasma, which is believed to be linked to changes in estrogen levels.5 Chloasma makes melanin in the skin more likely to react to sun exposure during pregnancy and menopause.


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Of course, a significant factor in how your skin reacts to these stimuli is your shade of skin tone. Skin color is affected by the amount of melanin in your skin baseline, and you can address these risks by understanding what your skin color is and how it responds to these factors.


The Fitzpatrick scale was developed in 1975 to establish an industry-standard index for degrees of skin pigmentation.6 Certain skin concerns are more common in specific skin types, such as the level of sensitivity someone might have to UV exposure. Knowing your skin type can help you anticipate and recognize stages of discoloration in your skin.


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Hyperpigmentation doesn’t happen overnight. It’s a process that begins deep within the outermost layer of your skin, the epidermis. On that level, cells called melanocytes undergo chemical reactions to develop skin pigment which deposits throughout the cell and then rises to the surface to become visible. There are three stages: activation, synthesis, and expression.


  1. Activation

    Discoloration stems from changes in melanin production in the skin. One of the several discoloration factors that can trigger melanocytes (pigmentation skin cells) deep in your epidermis to start working overtime.


  3. Synthesis

    Now that all systems are gone, melanocytes begin a series of reactions to produce extra melanin in response to a stimulus. Tyrosinase is an enzyme essential to melanin synthesis and converts the amino acid tyrosine to a chemical compound that leads to melanin. The number of amino acids present here determines if the discoloration is light or dark.7


  5. Expression

    The discolored melanosomes are deposited into the keratinocytes at the basale layer and eventually become visible on the surface of the skin.



We’ve discussed what can cause skin discoloration and how this hyperpigmentation happens in the body, but what does discoloration look like? Unless you are a newborn baby, your skin tells a story and embellishments like freckles are very common. While some identify freckles as a type of discoloration, they are a normal aspect of skin pigmentation. The kinds of discoloration we’re going to look at are more closely related to the effects of a damage or dramatic changes to your skin.


Age Spots

Age spots are concentrated spots of melanin that manifest similar to freckles though don’t fade the way freckles can.2,8 “Age spot” is a bit of a misnomer as these discolorations aren’t linked necessarily to aging but rather to sun exposure and build-up pigmentation over the years, making them more distinct as you age. Age spots develop in all Fitzpatrick skin types but can change intensity and color based on your natural skin tone.



Melasma is discoloration that usually appears on the face in patches. While there are different causes, it most commonly appears in pregnant women and is thought to be linked to hormones. Fitzgerald Types IV, V, and VI are most likely to get melasma as are those who have a genetic predisposition.7,9



As with many areas of skin health, a dermatologist is your best bet to receive a full diagnosis and medical treatment for a skin condition. Many consumers have concerns about the milder forms of hyperpigmentation and skin discoloration. Let’s take a quick look at ingredient technologies available in cosmetic products that target dark skin spots and other skin pigmentation issues. Each approach intervenes at a different stage of the discoloration process.


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As with so many elements of skin care and skin health, prevention is the most effective way of managing skin discoloration. UV rays are the main catalyst in many of the elements that cause increased melanin expression in skin, so staying out of the sun as much as possible and using sunscreens and sun covers is key. It’s impossible to fully reverse the effects of skin damage once it occurs but you can always do more to prevent it from happening in the first place.

Source: Nu Skin


  1. Chen Y, Lyga J. Brain-skin connection: stress, inflammation and skin aging. Inflamm Allergy Drug Targets. 2014;13(3):177-190. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4082169/
  2. Mayo Clinic. https://www.mayoclinic.org/diseases-conditions/age-spots/symptoms-causes/syc-20355859
  3. NewBeauty. https://www.newbeauty.com/can-stress-change-the-color-of-your-skin/
  4. Davis EC, Callender VD. Postinflammatory hyperpigmentation: a review of the epidemiology, clinical features, and treatment options in skin of color. J Clin Aesthet Dermatol. 2010;3(7):20-31. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2921758/
  5. Bolanca I, Bolanca Z, Kuna K, et al. Chloasma--the mask of pregnancy. Coll Antropol. 2008;32 Suppl 2:139-141. https://pubmed.ncbi.nlm.nih.gov/19140277/
  6. https://en.wikipedia.org/wiki/Fitzpatrick_scale
  7. https://www.aad.org/public/diseases/a-z/melasma-causes


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